In a landfill in the illegal settlement of Scrapyard, far below the mysterious space city of Zalem, the disgraced cyber doctor, Daisuke Ido makes a strange find: the detached head of a cyborg woman who has lost all her memories. He calls her Alita and equips her with a powerful new body, the Berserker. While Alita does not remember details of her previous life, a moment of despair awakens in her nerves the legendary martial arts school known as Panzer Kunst. In a place where there is no justice but what people do for themselves, Alita decides to become a killer-hunter, tracking and eliminating those who take advantage of the weak. But can he cling to his humanity as he begins to delight in his own thirst for blood?